The elderly matriarch of the Zhou family, grandmother of Zhou Yuzhi and Zhou Qinzhu. She has been unwell recently, and even imperial physicians were at their wit's end treating her. She is frail and suffers from chest pain and coughing fits. She is furious upon hearing that Gu Ruanci returned unruly and disrespectful. She is the person the Little Medical Immortal was initially invited to treat.
